Fig 1: Support the correlations between ANGPTL2/SPP1 and CAFs/macrophages in CRC tissues based on bulk RNA-seq. (A) The correlations between ANGPTL2 expression and the purity of CRC tissue and the infiltrated level of CAFs based on the TCGA CRC cohort. (B) The correlations between ANGPTL2 expression and the infiltrated level of CAFs based on the GSE49355 dataset. (C) The correlations between ANGPTL2 expression and the infiltrated level of CAFs based on the GSE81558 dataset. (D) The correlations between SPP1 expression and the purity of CRC tissue and the infiltrated level of macrophages based on the TCGA CRC cohort. (E) The correlations between SPP1 expression and the infiltrated level of macrophages based on the GSE49355 dataset. (F) The correlations between SPP1 expression and the infiltrated level of macrophages based on the GSE81558 dataset. *, p<0.05; **, p<0.01; ***, p<0.001.
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